3,5-Difluorobromobenzene

CAS: 461-96-1 | PC1385 | 3,5-Difluorobromobenzene

Catalogue Number PC1385

Synonym(s): 1-Bromo-3,5-difluorobenzene

3,5-Difluorobromobenzene, also known as 1-Bromo-3,5-difluorobenzene (CAS number: 461-96-1) is manufactured, supplied and distributed worldwide by Apollo Scientific.

It has been used to synthesise 4-bromo-2,6-difluorobenzoic acid. 3,5-Difluorobromobenzene can also be used to synthesise sel... Read More

CAS Number

461-96-1

Commodity Code

2903998090

MDL Number

MFCD00010305

Purity
98%
Notes
Tetrahedron Lett., 37, 6551 (1996) lithiation @ -75C occurs at para-position generating an 84% yield of 4-bromo-2,6-difluorobenzoic acid after carboxylation.
Formula Weight
192.99 g/mol
Density
1.676 g/cm³
Melting Point
-27 °C
Boiling Point
140-141 °C
Ref Index
1.499
Flash Point
44 °C
Chemical Hazard
Flammable/Harmful/Irritant
GHS
Hazard Statements
H226: Flammable liquid and vapour.
H302: Harmful if swallowed.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H373: May cause damage to organs ({{{0|||message=<or state all organs affected, if known>|||filter=(_)?ORGAN_.+}}}) thr
Precautionary Statements
P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}. P271: Use only outdoors or in a well-ventilated area. P280: Wear {{{0|||message=<specify protection equipmen: hazard.P260: Do not breathe {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?INHAL_CONDITION_.+}}}. P271: Use only outdoors or in a well-ventilated area. P280: Wear {{{0|||message=<specify protection equipmen
MSDS
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FTIR
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Typical Batch COA
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Size
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Quantity
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100g
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250g
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Size 250g
Price £30.00
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Product Description

3,5-Difluorobromobenzene, also known as 1-Bromo-3,5-difluorobenzene (CAS number: 461-96-1) is manufactured, supplied and distributed worldwide by Apollo Scientific.

It has been used to synthesise 4-bromo-2,6-difluorobenzoic acid. 3,5-Difluorobromobenzene can also be used to synthesise selective antagonists of GluN2C/GluN2D. It has applications in pharmaceutical processes, such as the synthesis of COX-2 inhibitors as anti-inflammatory and anti-cancer drugs, as well as being used as an intermediate in liquid crystal materials.

Apollo Scientific is one of the UK's leading chemical manufacturers, suppliers and distributors, with over 25,000 compounds as potential precursors in stock, and more than 3,000 diverse compounds created in our UK labs.

If you have any questions about how to order 3,5-Difluorobromobenzene (CAS 461-96-1), please get in touch with our team today.