27th July 2020

 

We have extended our range of 2,2-Dioxido-1,2,3-oxathiazolidine to include new spiro and cyclic compounds – all available from our UK Labs.  Boc protected 2,2-Dioxido-1,2,3-oxathiazolidines are widely used to introduce amino alkyl chains on aromatic compounds and have been used in a range of medicinal chemistry project including par-1 receptor antagonists1 and glycogen synthase activators2

  1. Bolin, David Robert; Hayden, Stuart; Qian, Yimin; Thakkar, Kshitij Chhabilbhai WO2011067266 A1 2011.
  2. Stamford, Andrew W.; Yang, Zhi-Qiang; Maletic, Milana; Cai, Senlin; Duan, Xiaobang; Cao, Jianhua  WO2016060940 A1 2016

 

  OR18837  (4R)-2,2-Dioxido-4-methyl-1,2,3-oxathiazolidine, N-BOC protected 

  OR400340  (4R)-2,2-Dioxido-4- phenyl -1,2,3-oxathiazolidine, N-BOC protected

   OR41174  (4S)-2,2-Dioxido-4-methyl-1,2,3-oxathiazolidine, N-BOC protected

    OR52985  6-Oxa-5-thia-4-azaspiro[2.4]heptane 5,5-dioxide, N-BOC protected

      OR52997  3-Oxa-2-thia-1-azaspiro[4.4]nonane 2,2-dioxide, N-BOC protected

      OR54380  (1S,2S)-(-)-1,2-Diphenylethane-1,2-diamine

      OR70067  2,2-Dioxido-1,2,3-oxathiazolidine, N-BOC protected

     OR400335  (4S)-2,2-Dioxido-4- isopropyl -1,2,3-oxathiazolidine, N-BOC protected

        OR400336  (4R)-2,2-Dioxido-4-isopropyl-1,2,3-oxathiazolidine, N-BOC protected

        OR400337  (4S)-2,2-Dioxido-4- benzyl -1,2,3-oxathiazolidine, N-BOC protected

        OR400340  (4R)-2,2-Dioxido-4- phenyl -1,2,3-oxathiazolidine, N-BOC protected

        OR400805  (R)-4,5,6-Tetrahydro-3H-pyrrolo[1,2-c]oxathiazole 1,1-dioxide

        OR400820  (S)-4,5,6-Tetrahydro-3H-pyrrolo[1,2-c]oxathiazole 1,1-dioxide

        OR928848  4,4-Dimethyl-1,2,3-oxathiazolidine 2,2-dioxide, N-BOC protected

 

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