8th April 2020

 

Benzimidazoles are bicyclic, aromatic compounds constructed from a benzene fused with an imidazole ring.

Thanks to their structural similarities, benzimidazoles have been subject to investigation as isosteres for the indole moiety, particularly as serotonin receptor agonists. In addition to this, benzimidazole derivatives are prominent building blocks and scaffolds for a number of different pharmaceutically active compounds. A number are potent anthelmintics like Mebendazole and Albendazole, while others have been used as antihistamines. Other pharmaceutical properties of some benzimidazoles include HIV-1 inhibition and anti-tumour activity.

During April we are offering 10% off a range of novel, fluorinated benzimidazoles:

 

         PC32917    4-Bromo-2-[bromo(difluoro)methyl]-1H-benzimidazole 

   PC32918    5-Bromo-2-[bromo(difluoro)methyl]-1H-benzimidazole

       PC32919    2-[Bromo(difluoro)methyl]-4-fluoro-1H-benzimidazole

  PC32920    2-[Bromo(difluoro)methyl]-5-fluoro-1H-benzimidazole

        PC32921    2-[Bromo(difluoro)methyl]-4-chloro-1H-benzimidazole

   PC32922    2-[Bromo(difluoro)methyl]-5-chloro-1H-benzimidazole

       PC32923    2-[Bromo(difluoro)methyl]-4-(trifluoromethyl)-1H-benzimidazole

PC32924    2-[Bromo(difluoro)methyl]-5-(trifluoromethyl)-1H-benzimidazole 

      PC32925    2-[Bromo(difluoro)methyl]-4-(trifluoromethoxy)-1H-benzimidazole

   PC32926    2-[Bromo(difluoro)methyl]-5-(trifluoromethoxy)-1H-benzimidazole

    PC32929    2-[Bromo(difluoro)methyl]-4-nitro-1H-benzimidazole

  PC32930    2-[Bromo(difluoro)methyl]-5-nitro-1H-benzimidazole   

         PC32931    2-(Trifluoromethyl)-4-chloro-1H-benzimidazole

         PC32932    2-(Trifluoromethyl)-4-nitro-1H-benzimidazole

      PC32934    4-Bromo-2-(difluoromethyl)-1H-benzimidazole

     PC32935    5-Bromo-2-(difluoromethyl)-1H-benzimidazole

     PC32936    2-(Difluoromethyl)-4-chloro-1H-benzimidazole

     PC32937    2-(Difluoromethyl)-5-chloro-1H-benzimidazole

        PC32938    2-(Difluoromethyl)-4-nitro-1H-benzimidazole

        PC32940    2-(Difluoromethyl)-5-nitro-1H-benzimidazole

 

Search our store for our full range of benzimidazoles.

Heterocyclic Benzimidazoles
Fluorinated Benzimidazoles

 

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