Product Focus – Cyclopropyl Derivatives

The cyclopropyl ring exhibits a number of interesting properties, such as the polarity of the three carbon atoms, relatively short C-C and C-H bonds and enhanced π-characteristics of the C-C bonds. These allow the cyclopropyl moiety to bestow a range of beneficial effects on the drug molecules that contain it. Some examples of this are increased metabolic stability, enhanced potency, increased brain permeability and reduced off-target effects.

Other advantages include entropically more favourable binding to the receptor and conformational restriction of peptides and peptidomimetics to prevent proteolytic hydrolysis. This range of useful properties has led to the use of cyclopropyl-containing compounds in cardiovascular drugs, antidiabetics, autoimmune drugs, drugs for respiratory disorders, CNS active drugs, anti-cancer drugs, anti-virals and antibacterials.

During May, we are offering 10% off a range of cyclopropyl derivatives

4-Bromo-2-cyclopropylaniline OR407784-Bromo-2-cyclopropylaniline

 

3-(Cyclopropyl)thiophene OR40807 3-(Cyclopropyl)thiophene

 

2-Amino-6-cyclopropylpyridine OR42286 2-Amino-6-cyclopropylpyridine

 

3-Amino-5-cyclopropylpyridine OR42287 3-Amino-5-cyclopropylpyridine

2-Bromo-3-cyclopropylthiophene OR46744 2-Bromo-3-cyclopropylthiophene

 

5-Cyclopropyl-2-thiophenesulfonyl chloride OR48097 5-Cyclopropyl-2-thiophenesulfonyl chloride

 

2-Bromo-6-cyclopropylphenol OR51799 2-Bromo-6-cyclopropylphenol

 

4-Cyclopropylthiophene-2-sulfonyl chloride OR54824 4-Cyclopropylthiophene-2-sulfonyl chloride

 

3-(Cyclopropyl)benzoic acid OR938340 3-(Cyclopropyl)benzoic acid

2-Amino-3-cyclopropylpyridine OR952526 2-Amino-3-cyclopropylpyridine

 

 

https://store.apolloscientific.co.uk/product/2-bromo-4-fluoro-1-cyclopropylbenzene PC32944 2-Bromo-4-fluoro-1-cyclopropylbenzene

 

2-Bromo-6-fluoro-1-cyclopropylbenzene PC32946 2-Bromo-6-fluoro-1-cyclopropylbenzene

3-Cyclopropyl-2-fluoroaniline PC49415 3-Cyclopropyl-2-fluoroaniline

 

4-Cyclopropyl-2-fluoroaniline PC49416 4-Cyclopropyl-2-fluoroaniline

 

5-Cyclopropyl-2-fluoroaniline PC49417 5-Cyclopropyl-2-fluoroaniline

 

2-Cyclopropyl-6-fluoroaniline PC49418 2-Cyclopropyl-6-fluoroaniline

 

2-Cyclopropyl-3-fluoroaniline PC49419  2-Cyclopropyl-3-fluoroaniline

 

3-Cyclopropyl-5-fluoroaniline PC49421 3-Cyclopropyl-5-fluoroaniline

 

2-Cyclopropyl-5-fluoroaniline PC49423 2-Cyclopropyl-5-fluoroaniline

 

 

Search our store for our full range of Cyclopropanes.

Cyclopropanes
Heterocyclic cyclopropanes
Fluorinated cyclopropanes

Supporting Scientific Discovery

Apollo Scientific are a leading manufacturer and supplier of high quality research chemicals, supporting discovery across the global market.  

We specialise in the manufacture and supply of aromatic, heterocyclic and aliphatic compounds, fluorochemicals and life sciences reagents, and are dedicated to providing a high level of customer service.

As one of the UK’s most established chemical distributors, we have a global reach. 

With more than 25,000 products in stock and over 100,000 products listed on our website, look no further to buy research chemicals, organic building blocks, life sciences reagents, high purity inorganics, deuterated solvents, and spectroscopy consumables.

All of our compounds can be searched by CAS, catalogue number, substructure or similarity, and you can check compound availability, current prices and lead time information online.To speak to a member of our expert team about research chemical supply, manufacture or distribution, email sales@apolloscientific.co.uk or call +44 (0)161 406 0505.