News

Fluorine is the most electronegative of the elements and bonds very strongly to most other elements, including carbon, hydrogen and silicon. In combination with its relatively small steric footprint, this means that fluorine atoms can exert powerful effects within molecules and drastically alter their behaviour. Incorporating fluorine into organic molecules may impart enhanced metabolic stability, […]

We would like to share an update on working practices within Apollo during the current pandemic in line with the UK governments recommendation that businesses employing more than 50 people provide transparency to stakeholders on this issue. Apollo continues to act in strict accordance with the current recommendations and will continue to review on a […]

New Fluorinated Building Blocks now in stock Apollo Labs have manufactured a comprehensive range of rare bromotrifluorobenzene derivatives tailor-made to support your Med Chem and academic projects.       PC10514  3-Bromo-2,4,5-trifluorobenzoic acid     PC39455  6-Bromo-2,3,4-trifluorobenzaldehyde      PC48003  Methyl 5-bromo-2,3,4-trifluorobenzoate      PC48807  5-Bromo-2,3,4-trifluorobenzonitrile       PC48931  5-Bromo-2,3,4-trifluorobenzoic acid       […]

At Apollo, our mission is to be the socially responsible partner of choice in the manufacture and supply of high-quality research chemicals, helping to support discovery across the global market.     As part of the Central Glass Group, we are ideally placed in the market to support your R&D projects from your initial concept through […]

We are now offering DNA & RNA Extraction kits for fast and efficient isolation of nucleic acids from a wide range of biological materials. In addition, we can now offer Real-Time PCR Master Mixes – convenient enzyme mixtures for fast and reliable qPCR using probes, including TaqMan®, Scorpions® and molecular beacon probes. EXTRACTME GENOMIC DNA […]

The cyclopropyl ring exhibits a number of interesting properties such as copolarity of the three carbon atoms, relatively short C-C and C-H bonds and enhanced π-characteristics of the C-C bonds. These allow the cyclopropyl moiety to bestow a range of beneficial effects on drug molecules which contain it. Some examples of this are: increased metabolic […]

Benzimidazoles are bicyclic, aromatic compounds constructed from a benzene fused with an imidazole ring. Thanks to their structural similarities, benzimidazoles have been subject to investigation as isosteres for the indole moiety, particularly as serotonin receptor agonists. In addition to this, benzimidazole derivatives are prominent building blocks and scaffolds for a number of different pharmaceutically active […]

New Antibiotic Solutions now available from stock with 15% off all catalogue prices   Bringing high quality antibiotics in an easy to use liquid form means less time preparing reagents and more time on getting results. Having these items in a ready made state also means less exposure to hazardous materials meaning it’s safer for […]

Presented at ESOC-19, July 2019 by our Head of Research and Production UK, Achim Porzelle. Nowadays reactions performed on milligram scale are dominating the primary literature including patents. Reactions on scale larger than 5g are rarely reported. Can these milligram procedures be used to make 100g of a compound or more? What factors need to […]

Benzopyrans, also known as chromenes, are bicyclic heterocycles consisting of a benzene ring fused to a pyran. Along with its keto-derivatives, chromone and coumarin, the chromene structure is a common occurrence in nature, with a high proportion being biologically active. Considered to be privileged structures in medicinal chemistry the benzopyran motif can be found in […]

Dear Partner, Following on from our update last week, we have now implemented the next stage of our Business Continuity Plan following the updated advice from the UK government. As of 24th March, all of Apollo’s office based staff are now working remotely and our Bredbury site has been closed until further notice. We anticipate […]