News

Sulphonyl chlorides are one of the most frequently requested compounds as they are important intermediates in the synthesis of API’s. Because of that we have been working on scaling up one of our sulphonyl chlorides synthesis in the labs this month. Takes a while to get the all the glassware set up nice and tidy, […]

Throughout October we have discounted a range of organic, fluorinated and heterocyclic building blocks, including the following items:     OR5232  3-Bromo-4-nitroaniline    OR400429  4-Bromo-6-methoxy-1H-benzimidazole                PC1377  3-Bromo-2-fluorophenylacetonitrile        PC6257  3′-Bromo-4′-(trifluoromethoxy)acetanilide        PC7521  4-(Methylsulphonyl)-2-(trifluoromethyl)benzyl bromide    PC8617  7-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid          PC32721  2-Fluoro-6-iodobenzyl […]

With the chill of October approaching, Apollo Scientific is thrilled to offer some Scary Spooky Savings throughout the month. Every day one of our 6,000 life science reagents will be chosen at random and given a monster-sized discount for 24hours.  After this time, the discount will disappear and a new item will arise for offer. […]

Establishing new in-house methods to increase the range of available catalogue compounds is one of our key objectives in the Apollo Labs. We have recently worked on the selective mono-trifluoromethylation of highly volatile 1,2-diketones. Similar compounds have been made via trifluoromethylations using Ruppert’s reagent  in neat conditions. Scheme 1: The initial reaction Focusing on 2,3-butadion […]

Get the most reliable and specific results from your RNA samples using versions of AMPLIFYME Probe One-Step RT-qPCR Mix for fast and sensitive RNA detection in a single tube.   AMPLIFYME PROBE ONE-STEP NO-ROX RT-QPCR MIX BIBL0030 The AMPLIFYME Probe One-Step No-ROX RT-qPCR Mix – created for reproducible and efficient first-strand cDNA synthesis and subsequent […]

Produced naturally by a range of bacteria and commonly synthesised via the Wohl-Aue reaction, phenazines are a class of nitrogen-containing heterocyclic compounds of wide interest. They have shown potential in biotechnological roles based on their ability to shuffle electrons and have also displayed antibiotic, antitumor and anti-parasitic activity.   Appl Microbiol Biotechnol. 2010;86(6):1659-1670. doi:10.1007/s00253-010-2509-3   […]

Our Labs are working on new pyridine series at the moment. Some tough nuts to crack! But we’ve had some success and the first new compounds have hit our store and are available from stock now.            PC50022  2-Methoxy-4-(trifluoromethyl)nicotinic acid      PC50183  5-Bromo-3-nitro-2-(trifluoromethyl)pyridine     PC50184  5-Bromo-3-iodo-2-(trifluoromethyl)pyridine      PC55436  […]

Q. Which currency am I able to pay in? A. We accept payment in GBP, EUR and USD.   Q. Can I buy through a distributor? A. Yes you can! Please click here for our list of distributors. We do sell directly to end users internationally so purchases can also be made directly with us. […]

Pyrazole compounds have a relatively low abundance in nature, but have a high synthetic availability. They have a long history of interest within medicinal chemistry and pharmaceutical development, with reports of investigation into their anti-inflammatory properties from over 50 years ago. The Pyrazole motif features in a wide range of pharmaceutical products from anti-cancer agents, […]

We have extended our range of 2,2-Dioxido-1,2,3-oxathiazolidine to include new spiro and cyclic compounds – all available from our UK Labs.  Boc protected 2,2-Dioxido-1,2,3-oxathiazolidines are widely used to introduce amino alkyl chains on aromatic compounds and have been used in a range of medicinal chemistry project including par-1 receptor antagonists1 and glycogen synthase activators2 Bolin, […]

Apollo have recently added Capricorn Scientific’s range of cell culture media, sera, and reagents to our rapidly expanding range of products for Life Science research as part of a non-exclusive distribution agreement. The mission of Capricorn Scientific is to provide quality cell culture media components, products, and services using the highest safety and compliance standards, […]

Alkynes are versatile molecules which can undergo a variety of reactions. As well as being widely used in Sonogashira coupling reactions, these compounds can also be utilised in Huisgen 1,3-dipolar cycloaddition (click chemistry), along with azides, to form 1,2,3-triazoles, whilst hydration of alkynes provide ketone products. During July we are offering 20% off a range […]