Go 6976

CAS Number: 136194-77-9
Commodity Code: 2933998090
MDL Number: MFCD00236434
Notes: Novel, very potent PKC inhibitor with high selectivity for the A-group of PKC isotypes (alpha, beta, and gamma), with IC50 values in the 2-10 nM range. Little or no inhibition of the B- and C-groups of PKC isotypes, even at much higher concentrations. Bioorg. Med. Chem. Lett. 3: 1959-1964 (1993).

Chemical Hazard: Irritant
GHS
Hazard Statements: H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statements: P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}. P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothi: hazard.P261: Avoid breathing {{{0|||message=<specify applicable conditions>|||default=dust/fume/gas/mist/vapours/spray|||filter=(_)?P261_INHAL_CONDITION_.+}}}. P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothi